Prevalence of dentin hypersensitivity: systematic review and meta-analysis. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste delivers instant* and long-lasting sensitivity relief plus gum protection. We observed the varying treatment response at different efficacy intervals that could be due to the varying degree of patient's response to pain-provoking stimuli in DH. who examined FCPS and Pro-argin formulations in 2018. SHOULD A PATIENT CONTINUE USING Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE ONCE THE DENTINE SENSITIVITY HAS GONE? Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief . The findings agreed with another in vitro trial by Mahmoodi et al. J Oral Rehabil. Clinically proven amino acid formula with Pro-Argin technology to provide sensitivity relief. Colgate Sensitive Pro Relief Whitening for improved stain removal. The Gum Health Physical is a new interactive digital tool you can use to quickly evaluate your patients in-office, and give them a personalized report they can use at home. J Dent. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial, https://doi.org/10.1186/s12903-021-01864-x, https://clinicaltrials.gov/ct2/show/NCT04249336, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. The second objective of the current study was to directly compare the clinical efficacy of FCPS, Pro-argin technology, and strontium acetate-based dentifrices due to their similar mode of action and tubular occluding potential in managing DH [36, 37]. Instant relief when applied directly to the sensitive tooth with the fingertip and gently massaged for 1 minute. These participants were randomized equally by the principal investigator into four entitled treatment arms using computer-generated random sequence numbers, and treatments were allocated randomly using sequentially numbered, opaque, sealed, and stapled envelopes (SNOSE). Pro-Argin technology can be found in Colgate Sensitive Pro Relief Toothpaste, sold as Colgate Sensitive Instant Relief in the UK and elmex Sensitive Professional in Europe. SCASS and VAS were introduced on each visit as primary and secondary outcome measures, respectively. YYYY Colgate-Palmolive Company. 1,2 This toothpaste contains a unique formula that blocks the pathways to pain instantly Its clinically proven formula provides INSTANT RELIEF from the first usage, LONG-LASTING RELIEF with twice everyday use. Clinically proven Instant and lasting Sensitivity relief*. Sealed channels protect against pain caused by hot, cold and sweet stimuli. Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Post-application changes on SCASS were observed after one minute, three days, two, four, and six weeks, subsequently. 2012;12(3):2208. 2017;9(4):e503. 1). Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. Pro-Argin Technology works through a natural process of dentin tubule occlusion that attracts arginine and calcium carbonate to the dentin surface to form a protective seal that provides instant relief.2 Directions *For instant relief, apply directly to the sensitive tooth with fingertip, and massage gently for 60 seconds, one a week or less frequently **For lasting relief, apply to a gentle toothbrush making sure to brush all sensitive areas of the teeth. Shiau HJ. Indian J Dent Sci. 2008;29(8):1S-35S. The New Colgate Sensitive Instant* Relief Repair & Prevent Toothpaste starts blocking sensitivity pain instantly*. The loss of tooth enamel is the most common cause of tooth sensitivity and is not affected by cavities, gum disease, or other problems. The maximum sampling time was 15min. YYYY Colgate-Palmolive Company. Clinical efficacy of BioMin F, Colgate sensitive pro-relief and Sensodyne rapid action dentifrices in DH [Internet]. Compared to stannous fluoride/sodium fluoride and novamin/sodium fluoride. J Clin Dent. Google Scholar. Douglas-de-Oliveira DW, Vitor GP, Silveira JO, Martins CC, Costa FO, Cota LOM. Colgate Sensitive Pro Relief Instant Relief, Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. Anvnd tv gnger dagligen. Colgate Toothpaste relieves the discomfort of tooth irritation by still addressing the root causes. Colgate Sensitive Pro-Relief Whitening Toothpaste provides clinically proven instant and lasting relief for sensitive teeth. Lai et al. Colgate Sensitive Pro-Relief toothpaste is a revolutionary and one-of-its kind remedy that can provide consumers suffering from Sensitivity the much needed instant and long lasting relief . The secondary analysis population could be described as 20 participants per treatment group out of 35 enrolled in the six-week trial who responded to mechanical and water jet stimuli on VAS with scores of4 as secondary outcome measures. A total of 140 participants were initially enrolled and randomised into the four treatment arms, with thirty-five in each group. A study evaluating the efficacy of strontium acetate relative to arginine-based dentifrices was conducted by West et al. 2017;30(4):2216. We discuss how this innovative technology works to provide patients with rapid and long-lasting relief from dentin hypersensitivity. Comparing the efficacy in reducing dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a commercial sensitive toothpaste containing 2% potassium ion: an eight-week clinical study on Canadian adults. Am J Dent. Gillam D, Hill R, Samueli A. Bioactive glasses in the management of dentine hypersensitivity: a review. Two double-blind randomized clinical studies by Nathoo et al. ID: NCT04249336 (https://clinicaltrials.gov/ct2/show/NCT04249336), Date of Registration: January 30, 2020 (Retrospectively registered). Helps repair teeth by forming a mineral layer that re-constructs the sensitive part of the tooth, with regular use; Seals the open nerve channels for instant relief, and helps prevent sensitivity from re-occurring; Plus the freshness you trust from Colgate Dentin hypersensitivity (DH) is a sharp toothache that influences a patients' oral health-related quality of life. It is clinically proven for instant and lasting Sensitivity relief* How does it work? These findings were similar to a previous study conducted by Schiff et al. Table 3 demonstrates the percent change in the mean scores of DH on SCASS relative to baseline within the group for each treatment arm. The mean scores with repeated measures were statistically analysed at each time point for study outcomes. If symptoms persist, talk to your healthcare professional. Lavender SA, Petrou I, Heu R, Stranick MA, Cummins D, Kilpatrick-Liverman L, et al. BMC Oral Health Martins C, Firmino R, Riva J, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. Children 6 years and younger: use a pea-sized amount for supervised tooth brushing to minimise swallowing. Ingredients *Calcium carbonate *Water All rights reserved. Hines D: Poster #0742 March 2018 AADR. Desensitizing toothpastes depolarize the nerves to reduce pain signals to the brain, while occlusives block the dentin tubules to prevent painful stimuli affecting dentinal fluids. The limitation of our study is that fluoridated dentifrice was used as a control which, although regarded as not possessing any desensitising effects. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. 1). Another study by Hines et al. https://doi.org/10.17352/2394-8418.00003. Tel: +381 (0)21 452-910, +381 (0)21 420-758. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. J Dent Res. Colgate Sensitive Pro-relief Instant Relief. Colgate Total with stannous fluoride also offers more benefits than ever before, including sensitivity relief, improved enamel strength* and odor neutralization* (*based on in vitro studies).Colgate Total Advanced Whitening is a tooth whitening toothpaste that provides stain removal and prevention. Click here. After six weeks, Pro-argin-based dentifrices showed greater clinical efficacy with mean scores (2.151.92) than other treatment arms for mechanical stimulated DH. Poster #3406, July 2018 IADR. OTC dentifrices with Pro-argin and strontium acetate are effective for immediate pain relief from DH, and FCPS could be the best possible treatment option for long term management of DH. J Clin Periodontol. Dentin hypersensitivity. Ashwini S, Swatika K, Kamala DN. Table 6 presents the change in the mean scores on VAS against waterjet stimulus from baseline to subsequent efficacy interval within each treatment arm. The sensitive toothpaste works in different ways to fight cavities, remove plaque, promote gum health and freshen breath. The prime focus of treatment nowadays is based on the exploration of novel materials to remineralise the exposed tubular endings and mimic and restore the structure of the dentin [11]. Mantzourani M, Sharma D. Dentine sensitivity: past, present and future. By using this website, you agree to our was used for statistical analysis. Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste with PRO-ARGIN Technology and Zinc provides clinically proven instant* and lasting sensitivity relief1-2 plus lasting gum protection3. Bakri MM, Hossain MZ, Razak FA, Saqina ZH, Misroni AA, Ab-Murat N, et al. Bae J-H, Kim Y-K, Myung S-K. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta-analysis. Therefore, this trial was planned to investigate the clinical efficacy of Pro-argin and strontium acetate for immediate pain relief in DH after one minute of topical application to fill the research gap associated with limited published evidence and risk of bias in selection, performance, attrition, and reporting as predicted by Pessoa et al. Arshad, S., Zaidi, S.J.A. However, Pro-argin formulation showed 8% more improvement in clinical symptoms of DH than strontium acetate formulation one minute after application. Learn more about caries in children from the resources provided on this page. Dentinal tubules occluded by bioactive glass-containing toothpaste exhibit high resistance toward acidic soft drink challenge. Trials. CONSORT flow chart. Docimo R, Montesani L, Maturo P, Costacurta M, Bartolino M, DeVizio W, Zhang YP, Cummins D, Dibart S, Mateo LR: Comparing the Efficacy in Reducing Dentine Hypersensitivity of a New Toothpaste Containing 8.0% Arginine, Calcium Carbonate, and 1450 ppm Fluoride to a Commercial Sensitive Toothpaste Containing 2% Potassium Ion: An Eight-Week Clinical Study in Rome, Italy. Statistical Package for the Social Sciences software v.21.0. Colgate Professional has resources to help your patients understand what causes enamel erosion and how to avoid falling into those traps. 1. 2009;20(1):106. They explored greater tubular occlusion potential and more acid resistance of Pro-argin in comparison to FCPS after subsequent seven days of application on dentinal discs [38]. The relief from sensitivity offered by Colgate Sensitive Pro Relief is proven to last. Help Caregivers Understand Caries | Colgate Professional, compared to a leading brand of desensitizing toothpaste, Colgate Sensitive Pro Relief Repair and Prevent, Colgate Sensitive Pro Relief Enamel Repair, Colgate Sensitive Pro Relief Multi Protection. Toothpaste doesn't only clean your teeth; we have products to help with a variety of tooth issues like sensitivity and more. 2020;12(2):87. If the enamel is too thin, has tiny tubules that reveal the underlying dentin, or is worn down in some places. 2015;28(1):404. Comparative evaluation of the efficacy of three commercially available toothpastes on dentin hypersensitivity reduction: an 8-week clinical study. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste for the daily oral care of patients with dentine hypersensitivity and gum problems. J Clin Periodontol. Table 5 presents the change in the mean scores of VAS against mechanical stimulus from baseline to subsequent efficacy interval within each treatment arm. 2018. 2010;21(2):568. A toothbrushing demonstration model from Nissin Company specification [PE-ORT002] was used to explain to the study participants about applying OTC dentifrices for one minute with the participant's finger. Plus it has the freshness you trust from Colgate! Use regularly to enjoy long-lasting relief from sensitivity*. fluorides, arginine, strontium, and bioactive glasses (BAG) [4] and in-office application of bioactive formulations such as glutaraldehyde, resin-based bonding agents and restorative materials, amorphous calcium phosphate based-tooth mousse, and lasers in the dental clinics [5]. Colgate Sensitive Pro Relief was compared to a leading brand of desensitizing toothpaste containing stannous fluoride in a laboratory study, with confocal laser scanning microscopy and a novel imaging program used to qualify dentinal tubule occlusion. 2016;3(1):0504. Colgate Sensitive Pro Relief Multi Protection, offering all of the above benefits in one convenient formula. For more great Dental Care products like toothpaste and mouthwash, continue browsing online and buy in-store at B&M. Colgate Sensitive Instant Relief Toothpaste 75ml Product code: 326795 2.49 Subject to availability - visit your nearest store If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. The study's primary objective was to investigate pain relief in one minute after topical application of Pro-argin and strontium acetate on sensitive teeth in DH. Get the best deals for COLGATE Sensitive Pro Relief Complete Protection Toothpaste 110g. However, FCPS formulation showed 1% more improvement than Pro-argin and 7% more than strontium acetate-based dentifrices. A total of 140 met the eligibility criteria with at least two sensitive teeth anterior to molars due to erosions or abrasions with or without an associated gingival recession. However, they also suggested further comparative evaluations of two dentifrices with large sample sizes as limited scientific evidence was found in previous studies [16]. Layer T, Hughes N. Evidence for the efficacy of an 8% strontium acetate dentifrice for instant and lasting relief of dentin hypersensitivity. 4.2 5 0 221 221 Colgate Sensitive Pro-Relief Enamel Rebuild toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. Colgate Sensitive Pro-Relief Instant Relief Sensitive Toothpaste - 75ml More Images Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. 4.4 5 0 198 198 Colgate Sensitive Pro-Relief Gum Therapy toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. # In-vitro study, actual confocal images after 5 treatments. If symptoms persist, talk to your healthcare professional. Use regularly to enjoy long-lasting relief from sensitivity*. Width 17 Height 5 Depth 3.8 Show More Payment & Refunds However, strontium acetate can potentially obliterate dentinal tubules by replacing the calcium ions of hydroxyapatite crystal lattice structure withstrontium ions along with its nerve depolarisation treat DH [7]. PREVENTS SENSITIVITY COMING BACK: Sealed channels protect against pain for instant relief, and with regular use provide lasting protection to prevent sensitivity from . Table 2 presents descriptive statistics of the primary analysis population as the primary statistical analysis was performed for 47 males and 81 females of age ranging from 18 to 50years with a mean age of 34.18.9. [28] reporting the immediate effect of 8% strontium acetate in alleviating clinical symptoms of DH with clinically and statistically significant (<0.001) measures relative to baseline [26]. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. A randomised clinical trial on the efficacy of 5% fluorocalcium phosphosilicate-containing novel bioactive glass toothpaste. * with direct application and daily brushing Benefits Exclusive Pro-Argin formula Prevents sensitivty coming back Plain bi-carb soda and coconut butter do a far better job at cleaning and desensitising. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste contains Sodium Fluoride (1450ppmF) the recommended fluoride level for effective caries prevention.4. WHAT IS THE FLUORIDE CONTENT OF Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE? J Dent. Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste provides instant* and long-lasting sensitivity relief and lasting gum protection: PRO-ARGIN Technology repairs sensitive areas of the teeth for instant and long-lasting pain relief1,2, Zinc helps to strengthen gums and to prevent recession a key cause of sensitivity3. J Clin Dent 2009; 20 (Spec Iss): 123-130. The main etiological factors are abrasion and erosion that may or may not be associated with gingival recession in DH. Am J Dent. Aust Dent J. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. Participants were asked to pick up the envelope from the box. The treatment difference between Pro-argin and 8% strontium acetate was not statistically significant with a p>0.05 for immediate and sustained pain relief in DH and statistically significant relative to control on all clinical parameters of the SCASS and VAS. 2. Therefore, the current study outcomes were analysed by parametric and non-parametric statistical tests after assessing the normal distribution of data and equality of variances with Shapiro Wilk statistics. HOW DOES Colgate SENSITIVE INSTANT Relief Repair & Prevent WORK? Cookies policy. Article it is in a rubbish bin now. While 8% strontium acetate showed a greater clinical reduction in water jet stimulated DH on VAS than Pro-argin at all efficacy intervals, as demonstrated in Table 6. 2009;22(Spec No. The secondary objective of the study was to compare the clinical efficacy of Pro-argin, strontium acetate, and FCPS for immediate and sustained treatment response in DH that was measured on SCASS as a primary outcome measure and VAS as secondary outcome measure at efficacy intervals of one minute, day-three, week two, four and six. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. (Table 1) (Fig. Free postage. IADR, The Excel, United Kingdom. Follow the directions for use. Frequency of dentin hypersensitivity: a cross-sectional study. There was a significant (p<0.001) reduction of 45.7% with Pro-argin, 37.6% with 8% strontium acetate, 18.1% with FCPS, and 15.2% with NaF-based dentifrices relative to baseline on SCASS after one-minute application on sensitive teeth. Naturally, the researchers wondered whether it could help shield a person from acquiring the virus. There was statistically no significant difference in the baseline characteristics of gender, age, baseline mean scores of clinical parameters of SCASS, and VAS used for mechanical and water jet stimuli between the four treatment groups (p>0.05). These dentifrices were extracted in a plain tube by the dental assistant from commercial packing and labelled with treatment codes to keep the principal investigator and participants blinded at the time of treatment assignment. Product Details Page . Can be used after the Colgate Sensitive Pro-Relief Desensitizing Paste. Google Scholar. In this way, variability in individuals' pain response was tried to be controlled and will be discussed in part 2 of this manuscript. Effectiveness of dentifrices with new formulations for the treatment of dentin hypersensitivitya meta-analysis. Terms and Conditions, This binds to the negatively charged dentine surface like a magnet. A 3-day randomised clinical study investigating the efficacy of two toothpastes, designed to occlude dentine tubules, for the treatment of dentine hypersensitivity. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (4.201.70) followed by strontium acetate (4.651.87) followed by FCPS (5.101.88) one minute after application. volume21, Articlenumber:498 (2021) 2020;99(5):51422. In each study, a single fingertip application of Colgate Sensitive Pro Relief was found to provide significant immediate relief relative to the comparative toothpaste, a result that was maintained over the subsequent three days with twice-daily brushing with the same toothpaste. compared Colgate Sensitive Pro Relief to another leading brand that desensitizes with a 2% potassium ion formula. 2013;41:S317. IRB-1351/DUHS/Approval/2019/184. All participants were instructed to dry the tooth surface with the cotton ball and apply a paste of about half-inch length on the dried surface for one minute, then brush the teeth twice daily after breakfast and before sleep as per directions demonstratedon the study model. Cunha-Cruz J, Wataha JC. Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly.